产品目录
Anti-SPIN2B Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108149P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 SPIN2B
是否单克隆
靶点
用途范围 Human Mouse Rat
形态
宿主 Rabbit
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108149P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 IHC
抗原来源
保质期
规格
产品用途 IHC
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
标识物
浓度 %
是否进口
Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin. On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line. Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity. In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth. There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.
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