产品目录
Anti-RICTOR Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K009413P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 RICTOR
是否单克隆
靶点
用途范围 Human Mouse Rat
形态
宿主 Rabbit
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K009413P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC IF ELISA
抗原来源
保质期
规格
产品用途 WB IHC IF ELISA
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
标识物
浓度 %
是否进口
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.
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