Anti-CNMD Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108200P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-07-19
产品详请
产地 北京
品牌 Solarbio
货号 K108200P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 IHC
应用范围 IHC
抗体名 CNMD
是否单克隆
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
宿主 Rabbit
纯度 %
亚型 IgG
浓度 %
是否进口
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
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