Anti-ANTXR1 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108224P
  • 价格: ¥1600/支
  • 发布日期: 2020-08-10
  • 更新日期: 2024-02-23
产品详请
抗体名 ANTXR1
是否单克隆
用途范围 Human Mouse Rat
宿主 Rabbit
纯度 %
产地 北京
品牌 Solarbio
货号 K108224P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB
产品用途 WB
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
浓度 %
是否进口
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
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