Anti-ANTXR1 Polyclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2024-11-06
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108224P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB
|
应用范围 |
WB
|
抗原来源 |
|
CAS编号 |
|
保质期 |
|
抗体名 |
ANTXR1
|
是否单克隆 |
否
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
|
形态 |
|
宿主 |
Rabbit
|
标记物 |
|
包装规格 |
|
纯度 |
%
|
亚型 |
IgG
|
标识物 |
|
浓度 |
%
|
免疫原 |
|
是否进口 |
否
|
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.