Anti-ZAP70 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108226P
  • 价格: ¥1600/支
  • 发布日期: 2020-08-10
  • 更新日期: 2023-12-06
产品详请
抗体名 ZAP70
是否单克隆
用途范围 Human Mouse Rat
宿主 Rabbit
纯度 %
产地 北京
品牌 Solarbio
货号 K108226P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB
产品用途 WB
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
浓度 %
是否进口
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
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