产品目录
Anti-MAPK14 Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108243P
  • 发布日期: 2020-08-10
  • 更新日期: 2022-02-09
产品详细说明
CAS编号
抗体名 MAPK14
是否单克隆
靶点
用途范围 Human Mouse Rat
形态
宿主
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108243P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB
抗原来源
保质期
规格
产品用途 WB
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
标识物
浓度 %
是否进口
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs); or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2; MEF2C; and MAX; cell cycle regulator CDC25B; and tumor suppressor p53; which suggest the roles of this kinase in stress related transcription and cell cycle regulation; as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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