Anti-MAPK14 Polyclonal Antibody
物品单位 |
价格 |
品牌 |
支 |
1600 |
Solarbio |
- 发布日期: 2020-08-10
- 更新日期: 2022-02-09
产品详细说明
CAS编号 |
|
抗体名 |
MAPK14
|
是否单克隆 |
否
|
靶点 |
|
用途范围 |
Human Mouse Rat
|
形态 |
|
宿主 |
|
标记物 |
|
纯度 |
%
|
免疫原 |
|
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108243P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
WB
|
抗原来源 |
|
保质期 |
|
规格 |
|
产品用途 |
WB
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human Mouse Rat
|
亚型 |
IgG
|
标识物 |
|
浓度 |
%
|
是否进口 |
否
|
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs); or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2; MEF2C; and MAX; cell cycle regulator CDC25B; and tumor suppressor p53; which suggest the roles of this kinase in stress related transcription and cell cycle regulation; as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.