Anti-CDKL1 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108246P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-05-17
抗体名 CDKL1
用途范围 Human Rat
纯度 %
产地 北京
品牌 Solarbio
货号 K108246P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC
产品用途 WB IHC
克隆性 Polyclonal Antibody
适应物种 Human Rat
亚型 IgG
浓度 %
The activation of signal transduction pathways by growth factors; hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis; kidney; brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However; unlike other MAP kinases; the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
Q Q: