Anti-CDKL1 Polyclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2025-04-28
产品详请
产地 |
北京
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品牌 |
Solarbio
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货号 |
K108246P
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保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB IHC
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应用范围 |
WB IHC
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抗原来源 |
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CAS编号 |
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保质期 |
|
抗体名 |
CDKL1
|
是否单克隆 |
否
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Rat
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形态 |
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宿主 |
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标记物 |
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包装规格 |
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纯度 |
%
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亚型 |
IgG
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标识物 |
|
浓度 |
%
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免疫原 |
|
是否进口 |
否
|
The activation of signal transduction pathways by growth factors; hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis; kidney; brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However; unlike other MAP kinases; the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.