Anti-RAB11B Polyclonal Antibody
- 价格: ¥1600/支
- 发布日期: 2020-08-10
- 更新日期: 2023-12-06
产品详请
抗体名 |
RAB11B
|
是否单克隆 |
否
|
用途范围 |
Human Mouse Rat
|
宿主 |
Rabbit
|
纯度 |
%
|
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108052P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
WB
|
产品用途 |
WB
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human Mouse Rat
|
亚型 |
IgG
|
浓度 |
%
|
是否进口 |
否
|
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11B plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.