产品目录
Anti-RAB11B Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108052P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 RAB11B
是否单克隆
靶点
用途范围 Human Mouse Rat
形态
宿主 Rabbit
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108052P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB
抗原来源
保质期
规格
产品用途 WB
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
标识物
浓度 %
是否进口
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11B plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
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