Anti-TSG101 Monoclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2025-04-28
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K009420M
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB
|
应用范围 |
WB
|
抗原来源 |
|
CAS编号 |
|
保质期 |
|
抗体名 |
TSG101
|
是否单克隆 |
否
|
克隆性 |
Monoclonal Antibody
|
靶点 |
|
适应物种 |
Human Rat
|
形态 |
|
宿主 |
|
标记物 |
|
包装规格 |
|
纯度 |
%
|
亚型 |
IgG
|
标识物 |
|
浓度 |
%
|
免疫原 |
|
是否进口 |
否
|
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.