Anti-YOD1 Polyclonal Antibody
- 价格: ¥1600/支
- 发布日期: 2020-08-10
- 更新日期: 2023-12-06
产品详请
抗体名 |
YOD1
|
是否单克隆 |
否
|
用途范围 |
Human
|
纯度 |
%
|
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108419P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
IHC
|
产品用途 |
IHC
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human
|
亚型 |
IgG
|
浓度 |
%
|
是否进口 |
否
|
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation.