Anti-YOD1 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108419P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-05-17
产品详请
抗体名 YOD1
是否单克隆
用途范围 Human
纯度 %
产地 北京
品牌 Solarbio
货号 K108419P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 IHC
产品用途 IHC
克隆性 Polyclonal Antibody
适应物种 Human
亚型 IgG
浓度 %
是否进口
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. May recruit PLAA, UBXN6 and VCP to damaged lysosome membranes decorated with K48-linked ubiquitin chains and remove these chains allowing autophagosome formation.
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