Anti-PPID Polyclonal Antibody
- 价格: ¥1600/支
- 发布日期: 2020-08-10
- 更新日期: 2023-09-21
产品详请
抗体名 |
PPID
|
是否单克隆 |
否
|
用途范围 |
Human Mouse Rat
|
纯度 |
%
|
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108429P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
IHC
|
产品用途 |
IHC
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human Mouse Rat
|
亚型 |
IgG
|
浓度 |
%
|
是否进口 |
否
|
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines.