Anti-OPTN Polyclonal Antibody
- 价格: ¥1600/支
- 发布日期: 2020-08-10
- 更新日期: 2023-09-28
产品详请
抗体名 |
OPTN
|
是否单克隆 |
否
|
用途范围 |
Human Mouse Rat
|
纯度 |
%
|
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108463P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
WB IHC
|
产品用途 |
WB IHC
|
克隆性 |
Polyclonal Antibody
|
适应物种 |
Human Mouse Rat
|
亚型 |
IgG
|
浓度 |
%
|
是否进口 |
否
|
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.