Anti-TTR Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108508P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-07-19
产品详请
产地 北京
品牌 Solarbio
货号 K108508P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 WB IHC
应用范围 WB IHC
抗体名 TTR
是否单克隆
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
纯度 %
亚型 IgG
浓度 %
是否进口
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome.
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