Anti-CUTA Polyclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2024-11-06
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108513P
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
IHC
|
应用范围 |
IHC
|
抗原来源 |
|
CAS编号 |
|
保质期 |
|
抗体名 |
CUTA
|
是否单克隆 |
否
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
|
形态 |
|
宿主 |
|
标记物 |
|
包装规格 |
|
纯度 |
%
|
亚型 |
IgG
|
标识物 |
|
浓度 |
%
|
免疫原 |
|
是否进口 |
否
|
CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. Existing as multiple alternatively spliced isoforms, CUTA functions as a homotrimer that is thought to act as a component of an acetylcholinesterase (AChE)-attached complex, suggesting an involvement in AChE regulation. The gene encoding CUTA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson’s disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.