产品目录
Anti-GCK Monoclonal Antibody
物品单位 价格 品牌
2080、3280 Solarbio
  • 产地:北京
  • 货号:K009428M
  • 发布日期: 2020-08-10
  • 更新日期: 2022-02-09
产品详细说明
CAS编号
抗体名 GCK
是否单克隆
靶点
用途范围 Human Mouse Rat Pig
形态
宿主
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K009428M
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC ELISA
抗原来源
保质期
规格
产品用途 WB IHC ELISA
克隆性 Monoclonal Antibody
适应物种 Human Mouse Rat Pig
亚型 IgG1
标识物
浓度 %
是否进口
Glucokinase (GCK) is a structurally and functionally unique member of hexokinase family. It is expressed only in mammalian liver and pancreatic islet beta cells. Because of its unique functional characteristics, the enzyme plays an important regulatory role in glucose metabolism.The rate of glucose metabolism in liver and pancreas is a function of the activity of the enzyme(PMID:1740341). Moreover, GCK has been found to have relationship with diabetes. Defects in GCK are the cause of maturity-onset diabetes of the young type 2 (MODY2) and familial hyperinsulinemic hypoglycemia type 3 (HHF3). It has 3 isoforms produced by alternative splicing with the same molecular mass of 52 kDa.
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