Anti-GCK Monoclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K009428M
  • 价格: ¥2080、3280/支
  • 发布日期: 2020-08-10
  • 更新日期: 2024-02-23
产品详请
抗体名 GCK
是否单克隆
用途范围 Human Mouse Rat Pig
纯度 %
产地 北京
品牌 Solarbio
货号 K009428M
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC ELISA
产品用途 WB IHC ELISA
克隆性 Monoclonal Antibody
适应物种 Human Mouse Rat Pig
亚型 IgG1
浓度 %
是否进口
Glucokinase (GCK) is a structurally and functionally unique member of hexokinase family. It is expressed only in mammalian liver and pancreatic islet beta cells. Because of its unique functional characteristics, the enzyme plays an important regulatory role in glucose metabolism.The rate of glucose metabolism in liver and pancreas is a function of the activity of the enzyme(PMID:1740341). Moreover, GCK has been found to have relationship with diabetes. Defects in GCK are the cause of maturity-onset diabetes of the young type 2 (MODY2) and familial hyperinsulinemic hypoglycemia type 3 (HHF3). It has 3 isoforms produced by alternative splicing with the same molecular mass of 52 kDa.
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