Anti-Caspase 3/P17/P19 Monoclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2024-11-13
产品详请
产地 |
北京
|
品牌 |
Solarbio
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货号 |
K009430M
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保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB IHC IF ELISA
|
应用范围 |
WB IHC IF ELISA
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抗原来源 |
|
CAS编号 |
|
保质期 |
|
抗体名 |
Caspase 3/P17/P19
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是否单克隆 |
否
|
克隆性 |
Monoclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
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形态 |
|
宿主 |
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标记物 |
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包装规格 |
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纯度 |
%
|
亚型 |
IgG1
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标识物 |
|
浓度 |
%
|
免疫原 |
|
是否进口 |
否
|
Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs the molecular mass of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.