Anti-Caspase 3/P17/P19 Monoclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K009430M
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-07-19
产品详请
产地 北京
品牌 Solarbio
货号 K009430M
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 WB IHC IF ELISA
应用范围 WB IHC IF ELISA
抗体名 Caspase 3/P17/P19
是否单克隆
克隆性 Monoclonal Antibody
适应物种 Human Mouse Rat
纯度 %
亚型 IgG1
浓度 %
是否进口
Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs the molecular mass of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.
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