Anti-KISS1 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K009431P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-06-21
产品详请
产地 北京
品牌 Solarbio
货号 K009431P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 WB IHC
应用范围 WB IHC
抗体名 KISS1
是否单克隆
克隆性 Polyclonal Antibody
适应物种 Human Mouse
纯度 %
亚型 IgG
浓度 %
是否进口
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.
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