Anti-BAX Monoclonal Antibody
- 价格: ¥2080、3280/支
- 发布日期: 2020-08-10
- 更新日期: 2023-12-06
产品详请
抗体名 |
BAX
|
是否单克隆 |
否
|
用途范围 |
Human Mouse Rat
|
纯度 |
%
|
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K009432M
|
保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
应用范围 |
WB IHC IF ELISA
|
产品用途 |
WB IHC IF ELISA
|
克隆性 |
Monoclonal Antibody
|
适应物种 |
Human Mouse Rat
|
亚型 |
IgG2b
|
浓度 |
%
|
是否进口 |
否
|
BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction. BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis.