北京索莱宝科技有限公司
产品展厅
Anti-BAX Monoclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K009432M
  • 发布日期: 2020-08-10
  • 更新日期: 2025-05-16
产品详请
产地 北京
品牌 Solarbio
货号 K009432M
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 WB IHC IF ELISA
应用范围 WB IHC IF ELISA
抗原来源
CAS编号
保质期
抗体名 BAX
是否单克隆
克隆性 Monoclonal Antibody
靶点
适应物种 Human Mouse Rat
形态
宿主
标记物
包装规格
纯度 %
亚型 IgG2b
标识物
浓度 %
免疫原
是否进口
BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction. BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis.
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