产品目录
Anti-BAX Monoclonal Antibody
物品单位 价格 品牌
2080、3280 Solarbio
  • 产地:北京
  • 货号:K009432M
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 BAX
是否单克隆
靶点
用途范围 Human Mouse Rat
形态
宿主
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K009432M
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC IF ELISA
抗原来源
保质期
规格
产品用途 WB IHC IF ELISA
克隆性 Monoclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG2b
标识物
浓度 %
是否进口
BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction. BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis.
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