Anti-EFNB1/2 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108408P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-06-21
产品详请
产地 北京
品牌 Solarbio
货号 K108408P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 WB
应用范围 WB
抗体名 EFNB1/2
是否单克隆
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
纯度 %
亚型 IgG
浓度 %
是否进口
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
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