Anti-RAD23A Polyclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2025-03-17
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108537P
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保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB
|
应用范围 |
WB
|
抗原来源 |
|
CAS编号 |
|
保质期 |
|
抗体名 |
RAD23A
|
是否单克隆 |
否
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Cow
|
形态 |
|
宿主 |
|
标记物 |
|
包装规格 |
|
纯度 |
%
|
亚型 |
IgG
|
标识物 |
|
浓度 |
%
|
免疫原 |
|
是否进口 |
否
|
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC.Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.