产品目录
Anti-LAYN Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108559P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 LAYN
是否单克隆
靶点
用途范围 Human
形态
宿主
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108559P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 IHC
抗原来源
保质期
规格
产品用途 IHC
克隆性 Polyclonal Antibody
适应物种 Human
亚型 IgG
标识物
浓度 %
是否进口
Layilin is a recently cloned ~55-kDa membrane-binding partner for talin (Borowsky and Hynes, 1998 ) that is widely expressed in different cell types and tissue extracts. It is found in peripheral ruffles of spreading cells and is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments. Layilin colocalizes with talin in ruffles and binds to talin's ~50-kDa head domain (amino acids 280–435). Other parts of talin (the ~220-kDa tail fragment) can bind β-integrin cytoplasmic tails, vinculin, and F-actin and hence form an integrin-cytoskeleton linkage at sites of cell-substratum contact. Layilin's extracellular domain is homologous with the carbohydrate-recognition domains (CRD) of C-type lectins.
联系方式
手机:13720003930
电话:010-50973129
Q Q:
微信扫一扫