Anti-TNFRSF11B Polyclonal Antibody
- 发布日期: 2020-08-10
- 更新日期: 2024-09-14
产品详请
产地 |
北京
|
品牌 |
Solarbio
|
货号 |
K108571P
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保存条件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
用途 |
WB IHC
|
应用范围 |
WB IHC
|
抗原来源 |
|
CAS编号 |
|
保质期 |
|
抗体名 |
TNFRSF11B
|
是否单克隆 |
否
|
克隆性 |
Polyclonal Antibody
|
靶点 |
|
适应物种 |
Human Mouse Rat
|
形态 |
|
宿主 |
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标记物 |
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包装规格 |
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纯度 |
%
|
亚型 |
IgG
|
标识物 |
|
浓度 |
%
|
免疫原 |
|
是否进口 |
否
|
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.