产品目录
Anti-ELOB Polyclonal Antibody
物品单位 价格 品牌
1600 Solarbio
  • 产地:北京
  • 货号:K108609P
  • 发布日期: 2020-08-10
  • 更新日期: 2020-08-10
产品详细说明
CAS编号
抗体名 ELOB
是否单克隆
靶点
用途范围 Human Mouse Rat
形态
宿主
标记物
纯度 %
免疫原
产地 北京
品牌 Solarbio
货号 K108609P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC
抗原来源
保质期
规格
产品用途 WB IHC
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
标识物
浓度 %
是否进口
This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
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