Anti-CDC42 Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108651P
  • 价格: ¥1600/支
  • 发布日期: 2020-08-10
  • 更新日期: 2024-02-23
产品详请
抗体名 CDC42
是否单克隆
用途范围 Human Mouse Rat
纯度 %
产地 北京
品牌 Solarbio
货号 K108651P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 IHC
产品用途 IHC
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
亚型 IgG
浓度 %
是否进口
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
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