人胰岛素样生长因子结合蛋白5 Elisa试剂盒
  • 品牌:Solarbio
  • 产地:北京
  • 货号:SEKH-0510
  • 价格: ¥2600/盒
  • 发布日期: 2020-08-10
  • 更新日期: 2024-02-23
产品详请
产地 北京
保存条件 -20
品牌 Solarbio
货号 SEKH-0510
检测方法 双抗体夹心法
适应物种 Human
检测限 0.6 - 40 ng/mL
数量 999
用途范围 Human
纯度 %
样本 血清/血浆/细胞培养上清
应用 Elisa试剂盒
是否进口
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.
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