大鼠趋化因子(fractalkine/CX3CL1) Elisa试剂盒
- 价格: ¥2600/盒
- 发布日期: 2020-08-10
- 更新日期: 2023-12-06
产品详请
产地 |
北京
|
保存条件 |
-20
|
品牌 |
Solarbio
|
货号 |
SEKR-0082
|
检测方法 |
双抗体夹心法
|
适应物种 |
Rat
|
检测限 |
195.0 - 12,500 pg/mL
|
数量 |
999
|
用途范围 |
Rat
|
纯度 |
%
|
样本 |
血清/血浆/细胞培养上清
|
应用 |
Elisa试剂盒
|
是否进口 |
否
|
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.