大鼠CD86 Elisa试剂盒
  • 品牌:Solarbio
  • 产地:北京
  • 货号:SEKR-0083
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-04-24
产品详请
产地 北京
保存条件 -20
品牌 Solarbio
货号 SEKR-0083
检测方法 双抗体夹心法
适应物种 Rat
检测限 4.7-300 pg/mL
数量 999
用途范围 Rat
纯度 %
样本 血清/血浆/细胞培养上清
应用 Elisa试剂盒
是否进口
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.
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