大鼠CD86 Elisa试剂盒
- 价格: ¥2600/盒
- 发布日期: 2020-08-10
- 更新日期: 2023-09-21
产品详请
产地 |
北京
|
保存条件 |
-20
|
品牌 |
Solarbio
|
货号 |
SEKR-0083
|
检测方法 |
双抗体夹心法
|
适应物种 |
Rat
|
检测限 |
4.7-300 pg/mL
|
数量 |
999
|
用途范围 |
Rat
|
纯度 |
%
|
样本 |
血清/血浆/细胞培养上清
|
应用 |
Elisa试剂盒
|
是否进口 |
否
|
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. Recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy.