北京索莱宝科技有限公司
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人白细胞介素18受体辅助蛋白 Elisa试剂盒
  • 品牌:Solarbio
  • 产地:北京
  • 货号:SEKH-0394
  • 发布日期: 2020-08-10
  • 更新日期: 2024-12-06
产品详请
产地 北京
保存条件 -20
品牌 Solarbio
货号 SEKH-0394
用途 Human
检测方法 双抗体夹心法
CAS编号
保质期
适应物种 Human
检测限 15.6 - 1,000 pg/ml
数量 999
包装规格
标记物
纯度 %
样本 血清/血浆/细胞培养上清
应用 Elisa试剂盒
是否进口
IL?18 R alpha by itself binds IL-18 with low-affinity and IL-18 R beta does not bind IL-18 in vitro, co-expression of IL-18 R alpha and IL-18 R beta is required for high-affinity binding and IL-18 responsiveness. Human IL-18 R beta cDNA encodes a 599 amino acid (aa) residue precursor type I membrane protein with a 14 aa signal peptide, a 342 aa extracellular region containing three immunoglobulin-like domains, a single transmembrane domain and a 222 aa cytoplasmic domain. Human and mouse IL-18 R beta share 65% aa sequence identity. The expression of IL-18 R beta parallels that of IL-18 R alpha and is detected in numerous tissues including lung, spleen, leukocytes and colon.
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