人基质金属蛋白酶抑制剂3 Elisa试剂盒
  • 品牌:Solarbio
  • 产地:北京
  • 货号:SEKH-0512
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-06-21
产品详请
产地 北京
保存条件 -20
品牌 Solarbio
货号 SEKH-0512
用途 Human
检测方法 双抗体夹心法
适应物种 Human
检测限 62.5 - 4,000 pg/mL
数量 999
纯度 %
样本 血清/血浆/细胞培养上清
应用 Elisa试剂盒
是否进口
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14
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