Recombinant Mouse TREM-1/CD354-北京索莱宝科技有限公司

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Recombinant Mouse TREM-1/CD354

品牌：Solarbio

产地：中国北京索莱宝

货号：P00310-10ug

价格： ￥询价
发布日期： 2017-02-28
更新日期： 2024-04-26

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货号	P00310-10ug
品牌	Solarbio
是否危险化学品	否
型号	P00310-10ug
密度	g/cm3
产地/厂商	中国北京索莱宝
产品等级	合格品
纯度	%

产品说明

Recombinant Mouse Triggering Receptor Expressed On Myeloid Cells 1 is produced by our Mammalian expression system and the target gene encoding Ala21-Ser202 is expressed with a 6His tag at the C-terminus.

Accession : Q9JKE2

备注：

以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。

These protocols are for reference only. Solarbio does not independently validate these methods.

保存温度	-20℃
有效期	6个月
Known as	Triggering receptor expressed on myeloid cells 1; TREM-1; CD354; Trem1
Purity	Greater than 95% as determined by reducing SDS-PAGE
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background	Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain. TREM-1 associates with the adapter protein, DAP12, to deliver an activating signal. TREM-1 is expressed on blood neutrophils and monocytes, and the expression is up-regulated by bacterial LPS. TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock. It stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. TREM-1 is amplifier of inflammatory responses that are triggered by bacterial and fungal infections and are a crucial mediator of septic shock.
规格	10ug 50ug 500ug 1mg