Anti-NGFR Polyclonal Antibody
  • 品牌:Solarbio
  • 产地:北京
  • 货号:K108569P
  • 价格: ¥询价
  • 发布日期: 2020-08-10
  • 更新日期: 2024-06-21
产品详请
产地 北京
品牌 Solarbio
货号 K108569P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
用途 WB
应用范围 WB
抗体名 NGFR
是否单克隆
克隆性 Polyclonal Antibody
适应物种 Human Mouse Rat
纯度 %
亚型 IgG
浓度 %
是否进口
Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
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